Postdocs and PhD students​

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There are currently PhD and PostDoc positions available in our group:

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 I.) PhD and PostDoc positions in Genome Integrity

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    Apply for PhD position (deadline 13 April): 

    https://www.slu.se/en/about-slu/work-at-slu/jobs-and-vacancies/doktorand--i-vaxters-genomintegritet/

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II.) AGILE - Advanced Training for Next Generation Scientists in Spatio-Temporal Imaging of Plant Cells

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Looking to work with and learn from world-leading experts in plant cell imaging?

The newly funded Marie Curie Doctoral Network 'AGILE' has got 15 open PhD positions: https://www.msca-agile.eu/

Apply through the website: https://www.msca-agile.eu/recruitment/

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Project: 3D genome organization during Polycomb-mediated gene silencing in plants
Polycomb group (PcG) proteins are chromatin-modifying factors that contribute to the formation and maintenance of repressive chromatin states at target genes. Over the last decade, a clear link between PcG activity and 3D genome regulation has been established, revealing 3D contact networks between PcG-silenced genes. However, these findings are almost always based on correlation studies. In this project, we aim to investigate the functional interconnection between nuclear organization and PcG-mediated epigenetic silencing, using the plant PcG target FLC as a model. Our previous studies showed that physical clustering of FLC copies is triggered by vernalization (promotion of flowering by cold). We will further exploit our live imaging FLC–lacO system to determine which genetic components are required for the observed cold-induced physical clustering. Specifically, we will investigate the role of non-coding RNAs associated with FLC epigenetic silencing; assess whether clustering can confer epigenetic memory; and determine the functional relevance of FLC clustering in terms of transcriptional activity and flowering time. We will also explore whether clustering is exclusive to FLC loci or whether it involves other PcG-regulated targets in plants. The results will help integrate changes in nuclear organization with epigenetic regulation underpinning developmental and environmental responses in plants.
 

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